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Si-Yuan Tang

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Sep 2026

Dilution mode acts as a critical process parameter that reprograms lipid nanoparticle assembly and in vivo mRNA delivery.

Messenger RNA (mRNA)-loaded lipid nanoparticles (LNPs) are predominantly manufactured by microfluidic mixing, where extensive efforts have focused on optimizing upstream formulation and mixing parameters. In contrast, the influence of dilution methods on the final physicochemical properties and biological performance o...

Si-Yuan Tang, Lei Huang, Wu Wang et al. · 0 citations

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