Author

Sibel Acat

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Open access Aug 2026

Combined PD-L1/CD8 immune phenotyping in breast cancer: exploratory associations across molecular subtypes and insights into possible exhaustion-related immune dysfunction

Background Programmed death-ligand 1 (PD-L1) expression and CD8+ tumor-infiltrating lymphocyte (TIL) density are established biomarkers of tumor–immune interaction in breast cancer; however, the biological and prognostic significance of their combined assessment across molecular subtypes remains incompletely defined. T...

Burcu Sanal Yılmaz, Afife Uğuz, Sibel Acat et al. · Frontiers in Medicine · 0 citations

Open access Aug 2026

National Trends in Ambient Air Pollutants and Cause-Specific Mortality in Türkiye, 2018–2024: An Ecological Time-Trend Study

Ambient air pollution remains an environmental health concern, yet national evidence in Türkiye integrating multiple pollutants, WHO guideline exceedance, mortality patterns, and monitoring network changes is limited. We analyzed seven annual observations (2018–2024) for PM10, SO2, CO, NO2, and O3. For each pollutant-y...

Ömer Acat, Sibel Acat, Okan Imre · Atmosphere · 0 citations