Aug 2026
pH-triggered in situ mineralized NIR-II nanozyme hydrogel enables spatiotemporally controlled antibacterial therapy and microenvironment reprogramming for infected bone defect repair.
Infected bone defects remain a significant clinical challenge due to bacterial colonization-induced persistent inflammation, oxidative stress, and local acidification, which collectively impair bone regeneration. Conventional approaches, including antibiotic therapy and bone grafting, are often insufficient to concurre...
Kai-Wen Chang, Pei-Yu Lin, Ke Xue et al.
· Biomaterials Advances · 0 citations