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Author

Sihem Ait-Oudhia

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2 papers indexed here

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Review Open access Sep 2026

Pharmaceutical Industry Perspectives on Exposure‐Response Confounding in Large Molecule Therapeutics: Results From an IQ Consortium Survey

Exposure‐response (ER) analyses assessing the efficacy of large molecule therapeutics are often susceptible to confounding, where associations between drug exposure and patient disease severity can obscure true ER signals and complicate dose selection. To better understand the pharmaceutical industry perspectives on th...

Engie Salama, M. Lamba, Sihem Ait-Oudhia et al. · 0 citations
Review Open access Sep 2026

Integrating Patient-Centric Clinical Pharmacology and MID3 to Advance Biologic Development in Immune-Mediated Inflammatory Diseases.

Advances in biologics and model-informed drug discovery and development (MID3) are transforming the treatment of immune-mediated inflammatory diseases (IMIDs). By integrating pharmacokinetics and pharmacodynamics, MID3 enables mechanism-based, patient-centered strategies to optimize therapies, strengthen benefit-risk a...

Sihem Ait-Oudhia, Li Zhang, D. Pisal et al. · 0 citations

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