Review
Open access
Aug 2026
NLRP3 inflammasome in cardiovascular diseases: molecular mechanisms and advances in targeted drug research
The NLRP3 inflammasome plays a pivotal role in innate immune responses and has emerged as an important contributor to the pathogenesis of cardiovascular diseases (CVDs), including atherosclerosis, heart failure, myocardial infarction, and hypertension-related organ damage. Upon activation, NLRP3 promotes the maturation...
Tian-Qing Zhang, Li Luo, Kai-Lin Yang et al.
· Frontiers in Immunology · 1 citation