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Silvana Cristina Rodrigues da Silva

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Open access Jul 2026

CEREBROVASCULAR DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, CHANGES IN THE DIAGNOSTIC PROFILE, AND SOCIODEMOGRAPHIC INEQUALITIES, 2010–2024

Objective: To analyze temporal trends in cerebrovascular disease mortality in Brazil, considering changes in the diagnostic profile, sociodemographic characteristics, place of death, and regional distribution from 2010 to 2024. Methods: This was a nationwide ecological time-series study using data from the Mortality Information System (SIM/DATASUS). Deaths classified under codes I60 to I69 of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using absolute and relative frequencies and sex ratio. Results: A total of 1,526,062 deaths from cerebrovascular diseases were recorded, with a 4.1% increase between the first and last five-year periods. Unspecified stroke (I64) remained the leading cause, although its share declined from 43.0% to 33.5%. Conversely, cerebral infarction (I63) increased from 4.2% to 11.4%, and sequelae of cerebrovascular diseases (I69) from 16.5% to 18.6%, suggesting improved diagnostic specification. Mortality was concentrated among individuals aged 60 years or older, with a slight male predominance, proportional growth among Black and Brown populations, relative increase in the North Region, and hospital predominance. Conclusion: Mortality remains high and unequal, requiring cardiovascular prevention, improved stroke care pathways, rehabilitation, and reduction of regional inequities.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al. · 0 citations
Open access Jul 2026

CANCER MORTALITY IN BRAZIL: TEMPORAL TRENDS, CHANGES IN DIAGNOSTIC PROFILE, AND REGIONAL DIFFERENCES, 2010–2024

Objective: To analyze neoplasm mortality in Brazil according to temporal trends, diagnostic categories of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), sociodemographic characteristics, place of occurrence, and regional differences from 2010 to 2024. Methods: This was a nationwide ecological time-series study using data from the Mortality Information System (SIM/DATASUS). Deaths classified in the ICD-10 neoplasm chapter (C00–D48) were included and grouped into three five-year periods: 2010–2014, 2015–2019, and 2020–2024. Sex, age group, race/skin color, education, marital status, place of occurrence, macro-region, and main diagnostic categories were analyzed using absolute and relative frequencies and percentage variation. Results: There were 953,873 deaths in 2010–2014, 1,110,039 in 2015–2019, and 1,228,995 in 2020–2024, representing a 28.84% increase. Malignant neoplasms of the bronchi and lungs remained the leading cause of death, followed by breast, prostate, stomach, colon, and pancreatic cancers. Increases were observed for pancreatic, colon, kidney, multiple myeloma, bladder, and breast cancers. Deaths increasingly concentrated among individuals aged 60 years or older, with greater female participation, proportional growth among Black and Brown populations, and fewer missing records. Regionally, the Southeast maintained the highest absolute burden, while the North, Midwest, and Northeast showed the greatest proportional increases. Conclusion: Neoplasm mortality increased markedly in Brazil, reflecting population aging, epidemiological transition, regional inequalities, and the need to strengthen prevention, screening, early diagnosis, oncology care, surveillance, equity, and health information.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al. · 0 citations