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Author

Silvia Basili Franzin

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Open access Oct 2026

Engineered probiotic-mediated palmitoylethanolamide biosynthesis protects against colitis-associated liver injury

Chronic colitis promotes secondary liver injury through disruption of the gut–liver axis, whereby intestinal barrier breakdown enables portal translocation of microbial products that activate hepatic inflammatory and fibrogenic pathways. Palmitoylethanolamide (PEA), an endogenous ALIAmide acting primarily via PPAR-α, e...

Irene Palenca, Silvia Basili Franzin, G. Sarnelli et al. · 0 citations

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