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Author

Simin Chen

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Open access Jul 2026

Deletion of the c-di-GMP Phosphodiesterase BpdB Attenuates Brucella melitensis Virulence by Enhancing Oxidative Stress Sensitivity, Partially via the Host STING Signaling Pathway

It is demonstrated that BpdB contributes to B. melitensis virulence by enhancing oxidative stress resistance and dampening STING-dependent host responses, providing new insights into c-di-GMP-mediated host–pathogen interactions.

Na Li, Qiumei Shi, Simin Chen et al. · 0 citations

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