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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Simon d’Oelsnitz

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Open access Sep 2026

Biocatalytic Production of Galantamine in Yeast through Cytochrome P450 Optimization

Galantamine is a pharmaceutically relevant Amaryllidaceae alkaloid used for the treatment of Alzheimer’s disease. Its structural complexity and low abundance in plants motivate the development of alternative manufacturing routes. Here, we established the first engineered yeast platform for the biocatalytic production o...

Maxence Holtz, Samantha de Haan, Cecília Castellví Domingo et al. · 0 citations
Open access Jul 2026

Using enantioselective biosensors to evolve asymmetric biocatalysts.

This work evolves enantioselective transcription factors that convert enzyme-catalyzed enantiomer concentrations into programmable gene expression outputs, focusing on imine reductases, and designs a genetic circuit that enables TF generation within weeks.

Simon d’Oelsnitz, Wantae Kim, Nicole N Zhao et al. · 7 citations

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