Open access
Sep 2026
β-catenin activation in Wnt-responsive Axin2 + intercalated duct cells drives early epithelial and stromal remodelling in the adult murine submandibular gland
Adult salivary glands depend on a branched ductal network for secretion, yet the identity of Wnt-responsive ductal cells that support adult homeostasis and their relevance to early salivary gland lesion formation remain unclear. Using Axin2 CreERT2/+ ; R26 mTmG/+ mice for lineage tracing, together wit...
Araz Ahmed, Simon Whawell, I. Miletich
· Cell Communication and Signa... · 0 citations