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Author

Simona Lattanzi

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Open access Oct 2026

Beyond seizure control: Non-seizure-related outcomes in focal-onset epilepsy treated with adjunctive cenobamate. Third interim results from the BLESS study.

OBJECTIVE Cenobamate is approved for treatment of focal seizures in adults, but evidence on non-seizure outcomes remains limited. This interim statistical analysis of the cenoBamate in aduLts with focal-onsEt SeizureS (BLESS) study evaluated patient- and clinician-reported outcomes for up to 52 weeks of cenobamate trea...

Simona Lattanzi, G. d'Orsi, M. T. Di Claudio et al. · 0 citations
Open access Sep 2026

Statin use and risk of remote seizure after first new onset status epilepticus.

OBJECTIVE Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first-ever status epilepticus (SE) survivors. METHODS Retrospective analysis was made of adult patie...

Niccolò Orlandi, G. Giovannini, Lisa Taruffi et al. · 0 citations
Open access Aug 2026

Status epilepticus in adults: From etiology to treatment response.

Heterogeneity exists within the spectrum of acute symptomatic causes; distinct etiological subcategories may carry different risks of refractoriness and superrefractoriness.

Simona Lattanzi, G. Giovannini, Niccolò Orlandi et al. · 2 citations · ⚡1
Open access Jul 2026

A Predictive Model for Short-Term Mortality After Status Epilepticus

The ACARD score is a user-friendly tool developed to predict 30-day mortality after nonhypoxic SE and has the potential to identify participants at high risk of short-term mortality and outperform the performance of other available scoring systems.

Simona Lattanzi, E. Trinka, P. Bosque-Varela et al. · 0 citations

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