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Author

Simone Mulè

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2 papers indexed here

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Open access Sep 2026

Modulation of Hepatic Cholesterol-Related Pathways by Ophiocordyceps sinensis and Coenzyme Q10 in a Sequential Gut–Liver In Vitro Model

Dysregulated hepatic cholesterol handling and oxidative stress represent key targets for nutritional interventions. This study investigated a combination of Ophiocordyceps sinensis (formerly Cordyceps sinensis) extract and coenzyme Q10 (CoQ10) using a sequential gut–liver in vitro model. Differentiated Caco-2/HT29-MTX...

Simone Mulè, Rebecca Galla, Matteo Musu et al. · 0 citations
Open access Aug 2026

Effects of a Chemically Characterised Multi-Component Nutraceutical Formulation on Intestinal, Hepatic and Skeletal Muscle Responses in an In Vitro Gut–Liver–Muscle Model

Autophagy plays a central role in cellular homeostasis and metabolic adaptation, and its dysregulation has been implicated in metabolic disorders, including non-alcoholic fatty liver disease (NAFLD). This study investigated the biological effects of a chemically characterised multi-component nutraceutical formulation u...

Rebecca Galla, Francesca Parini, Simone Mulè et al. · 0 citations

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