Simrandeep Kaur

Supplementation of αKG along with TGFβ/HIF1α antagonist rescues lung fibrosis in mice with severe SARS-CoV-2 infection

The study demonstrated the upregulation signalling molecules like P-AKT, TGFβ and HIF1α and their association with pulmonary fibrosis in mice after severe SARS-CoV-2 infection and described the HIF1α axis as the therapeutic target in rescuing post-acute sequelae such as ARDS and fibrosis in mice with severe SARS-CoV-2...