Investigation of ABL Kinase Inhibitory Potential of Bioactive From Juglans Regia: Molecular Docking, Pharmacophore Modelling and Molecular Dynamics Simulation Study
Objective: The present study aimed to investigate the potential of phytoconstituents of Juglans regia derived from IMPPAT database as inhibitors of the Abelson tyrosine kinase (c-Abl), using in silico tools. Methods: Physicochemical and pharmacokinetic properties were predicted using QikProp, while toxicity profiles we...