Open access
Aug 2026
DEVELOPMENT AND VALIDATION OF AN RP-HPLC BIOANALYTICAL METHOD FOR QUANTIFICATION OF RIZATRIPTAN BENZOATE IN RAT PLASMA AND BRAIN HOMOGENATE: APPLICATION TO PHARMACOKINETIC AND BRAIN-TARGETING STUDIES
Purpose This study was conducted to establish and validate a new, rapid, specific, sensitive and reproducible reverse-phase high performance liquid chromatographic (RP-HPLC) method for the determination of Rizatriptan Benzoate (RZT) in rat plasma and brain homogenate. The validated method was then used to assess the PK...
Priyanka Das, Bipul Nath, Payal Dasgupta et al.
· Genetics and Molecular Resea... · 0 citations