Author

S.K. Paliwal

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Open access Sep 2026

Design and syntheses of 4-aminoquinoline-thiazolidinone hybrids as anti-protozoal agents

Introduction Molecular hybridization is an effective approach employed to synthesize molecules that possess the ability to function as dual inhibitors, thereby addressing the issue of growing resistance. Resistance by the malaria parasite is one such example. Therefore, the study aims to develop hybrid compounds consis...

G. N. Fatima, S. Paliwal, S. Saraf · Frontiers in Chemistry · 0 citations

Open access Jan 2026

Orbitrap HRMS-Based Comprehensive Metabolite Characterization of Duvelisib in Cross-Species Hepatocytes.

RATIONALE Duvelisib (DVB), a selective PI3K-δ/γ inhibitor approved for chronic lymphocytic leukemia, requires detailed metabolic characterization to support early drug development and selection of appropriate toxicology species. Because drug metabolism varies across species, an integrated system such as primary hepatoc...

B. Warkad, Swapnil Sharma, Prakash Niguram et al. · Rapid Communications in Mass... · 0 citations