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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Sobhi M. Gomha

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2 papers indexed here

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Oct 2026

Vonoprazan attenuates cyclophosphamide-induced ovarian injury in rats via modulation of TLR4/NF-κB and AMPK/SIRT1/Nrf2/HO-1 signaling.

Cyclophosphamide (CPA) is a widely used alkylating agent that causes premature ovarian insufficiency (POI), a major reproductive risk for young female cancer survivors. This study examined whether vonoprazan (VON), a potassium-competitive acid blocker with reported cytoprotective activity in non-gastric tissues, protec...

Al Shaimaa Mahmoud Kotb, Ehab E. Sharata, Reham H. Mohyeldin et al. · 0 citations
Open access Oct 2026

Strategic development of benzimidazole-derived glycosidase modulators for antihyperglycemic intervention: a comprehensive medicinal study integrating molecular docking, biological evaluation, in vivo validation and pharmacokinetic assessment.

Current in silico drug discovery workflows largely rely on ligand-based screening and structure-based molecular docking to identify enzyme inhibitors, often overlooking dynamic biological contexts that influence drug efficacy and stability. Integrating multiscale computational modeling with experimental validation at e...

Zanib Fiaz, Shoaib Khan, Tayyiaba Iqbal et al. · 0 citations

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