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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Somayeh Mojtabavi

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4 papers indexed here

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Oct 2026

Aniline-linked coumarin-triazole hybrids as α-glucosidase inhibitors: An insightful study from synthesis to in vivo efficacy and mechanistic analysis.

A new series of coumarin-aniline-triazole hybrids 12a-p was prepared using a multi-step approach. This synthesis involved a Knoevenagel condensation between 2-hydroxybenzaldehyde and diethyl malonate, followed by ester hydrolysis and amide coupling to yield a coumarin-based alkyne, which was then reacted with various 2...

Bahareh Bayati, M. Sadeghi Moghadam, Fariba Peytam et al. · 0 citations
Sep 2026

Phytofabricated Ag and ZnO Nanoparticles from Nonea lutea: Potent α-Glucosidase Inhibitory Activity and Multifunctional Biomedical and Environmental Applications

Both zinc oxide nanoparticles and silver nanoparticles evaluated for their antibacterial, antioxidant, photocatalytic, antiparasitic, antidiabetic, and sunscreen activities suggest that N@AgNPs and N@ZnONPs possess promising multifunctional biomedical potential.

Reza Dehghanpour Kalan, Elham Khayer Damirchi, M. Barari et al. · 1 citation
Open access Aug 2026

Novel diazene-tri(phenoxy-1,2,3-triazole-acetamide) derivatives as potent α-glucosidase inhibitors: synthesis, biological evaluation, and in silico studies

Kinetic enzyme assays revealed that compound 9f acts as a competitive inhibitor of α-glucosidase, competing with the natural substrate for binding to the active site, with a Ki value of 100 nM, and pharmacokinetic predictions showed that compound 9f exhibits a bioavailability radar and drug-likeness profile similar to...

Shahab Kermaninia, M. Sayahi, Mohammad Halimi et al. · 0 citations
Aug 2026

Design, synthesis, and in vitro/in vivo evaluation of novel diphenyl-1,2,4-triazine-3-yl-thioacetamide-chalcone hybrids as potent α-glucosidase inhibitors targeting type 2 diabetes.

Findings identify compound 9b as a promising lead α-glucosidase inhibitor with potent in vitro and in vivo antihyperglycemic activity, warranting further investigation for the treatment of type 2 diabetes.

Elika Salehi Ghalehsefid, Mohammad Halimi, Hassan Mohammadi et al. · 0 citations

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