The majority of patients with colorectal cancer (CRC) fail to respond to anti-PD-1/PD-L1 immunotherapy, highlighting an urgent need for alternative immunotherapeutic targets. The immunosuppressive ligand CD155 potently dampens natural killer (NK) cell cytotoxicity via inhibitory receptors, but how CRC cells sustain h...
Jiahe Xu, Dong-Ze Zhang, Kexi Yang et al.· Cell Death Discovery· 0 citations
Background Capecitabine stands as a pivotal chemotherapeutic agent in gastric cancer (GC) management. While its general safety profile has been documented, comparative pharmacovigilance analyses of distinct capecitabine-based treatment regimens among GC patients remain scarce. Methods This study extracted AE reports fr...
Ru-Bao Sang, Min Zhu, J. Mao et al.· Frontiers in Pharmacology· 0 citations
BACKGROUND
Generating high-quality CT images from cone-beam computed tomography (CBCT) is critical for clinical applications such as online adaptive radiotherapy (ART). Although deep learning methods, including diffusion models, have shown remarkable advances, persistent challenges remain in terms of image quality and...
Zhi-Bin Li, Li Chen, Guanghui Gan et al.· Medical Physics (Lancaster)· 0 citations
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