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Open access Aug 2026

Hepatic ChREBP Drives Cardiac Remodeling via ApoM Non-transcriptional Repression

BACKGROUND: Pathological cardiac remodeling is a hallmark of numerous cardiovascular diseases and develops into heart failure. As a systemic disease, effective treatments for cardiac remodeling from a tissue crosstalk perspective are still significantly unmet. METHODS: Hepatocyte-specific ChREBP (carbohydrate response...

Shuang Zhang, Zhen-zhen Zhang, Zi-Han Ma et al. · 0 citations
Review Open access 2026

Aging and Cardiovascular Health: CVIA State-of-the-Art Review

Aging is an inevitable biological process marked by progressive functional decline and elevated risk of cardiovascular diseases (CVDs). This review systematically examines the clinical mechanisms linking aging to cardiovascular pathology, focusing on molecular, cellular, and physiological changes that contribute to car...

Naiqi Liu, Weiwei Wang, Runzhao Miao et al. · 0 citations

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