Review
Open access
Aug 2026
Ferroptosis suppressor protein 1-mediated ferroptosis suppression in sepsis: non-canonical antioxidant pathways, inflammatory regulation, and therapeutic perspectives
Sepsis, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, remains a global health challenge characterized by high mortality and limited therapeutic options. Recent evidence identifies ferroptosis—an iron-dependent form of regulated cell death driven by the lethal accumul...
Yonghuan Tian, Zaiyong Li, Tian Tian et al.
· Frontiers in Immunology · 1 citation