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Oct 2026

Enantioselective Synthesis of Axially Chiral Tetraphenylethenes via NHC-Catalyzed Desymmetrization and Following Kinetic Resolution.

Herein, we report an efficient method for the enantioselective construction of axially chiral tetraphenylethylene (TPE) via N-heterocyclic carbene (NHC)-catalyzed desymmetrization of prochiral isophthalaldehyde-derived TPEs. Both aliphatic alcohols and phenols were well-tolerated, affording the atropisomeric TPEs in go...

Xin-Han Wang, Song Ye, Chun-Lin Zhang · 0 citations

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