Author

Songbo Li

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Review Open access Aug 2026

Pyroptosis and HMGB1 Signaling in T2DM-Related Sarcopenia: Current Evidence, Mechanistic Framework, and Exercise Implications

Current evidence for inflammasome- and gasdermin-related pyroptotic signaling, HMGB1-associated damage signaling and their potential relevance to diabetic skeletal muscle are summarized and exercise is discussed as a modulator of upstream metabolic and inflammatory stress.

Peng-Yu Fu, Yuxuan Shi, Songbo Li et al. · Health and Metabolism · 0 citations