Open access
Oct 2026
Synthesis, design and integrated in vitro/in silico assessment of novel cyano-amide derivatives
A novel and an efficient synthesis of a series of cyano-amide derivatives 3a-h was achieved via solvent-free reaction of benzylcyanide derivatives 1 with isocyanate derivatives 2 at room temperature. The produced components were structurally characterized by NMR spectroscopy multinuclear: 1 H and 13 C and e...
R. Omrani, Imen Kharmachi, Mohamed Amine Ben Abdallah et al.
· Arabian Journal of Chemistry · 1 citation