Patient-Specific Computational Framework to Spatiotemporally Forecast Treatment Response and Identify Biologically Informed Radiotherapy Targets in High-Grade Glioma
Purpose High-grade gliomas exhibit substantial spatial and temporal heterogeneity, posing a challenge for radiotherapy (RT) target definition. Adaptive RT, which prospectively modifies treatment plans, may benefit from early identification of intratumoral regions likely to exhibit differential treatment response. Appar...