Srilagna Chatterjee

Biosynthesis and characterization of a neuroprotective injectable copolymeric scaffold impregnated with GOQD-infused HA-collagen electrospun nanofibers: A strategy to prevent oxidative damage, plaque formation, and neurodegeneration.

The inhibitory effect of Scaffold 3 on Aβ-peptide aggregation was established, and it also disrupted the preformed amyloid plaque in cells and mitigated the induced oxidative stress, suggesting scaffold 3 can be projected as a suitable matrix to trigger neuronal-like cellular responses.