Rep3D : an algorithm to identify structurally similar motifs
Repeats in protein structures act as essential structural building blocks, commonly forming multiple complex structures and functional units. Identifying sequence repeats in the primary structure alone is not sufficient to find the function of the proteins. Therefore, a new method, repeats in the three-dimensional structure of proteins ( Rep3D ), has been developed using a dynamic programming approach. This method enables rapid and accurate identification of structural repeats by calculating the distance between Cα atoms in the peptide backbone. A standalone computing version of the tool has been developed and implemented in Python. The Rep3D source code, along with documentation, examples of use and instructions, is available in the Rep3D repository (https://github.com/srimaha0801/Rep3d-Stand_Alone_v1/).