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Author

Srinivas M. Tipparaju

2 papers indexed here

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Open access Sep 2026

Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT).

Nicotinamide phosphoribosyl transferase (NAMPT) activation is a key enzyme in the NAD+ salvage pathway that mediates major metabolic changes in skeletal muscle and during aging. The Nampt activator P7C3 provides beneficial effects to both cardiac and skeletal muscle in diabetes, but the effects on aging remain unknown....

Ravikumar Manickam, Gaurav Shingote, Janani Prasanna et al. · 0 citations
Open access Sep 2026

Extracellular vesicles from specific muscle progenitor cells as a novel therapeutic strategy for sarcopenia

Sarcopenia, characterized by age-related loss of skeletal muscle mass and function, poses a significant challenge to lifelong health and wellbeing. Currently, no effective therapeutic interventions exist. In previous work, we developed specialized muscle progenitor cells (MPCs), termed Givi-MPC, from human induce...

Bi Zhao, Yao Yao, Hong Shi et al. · 0 citations

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