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Author

Stefan D. Anker

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Oct 2026

Echocardiographic estimates of pulmonary artery acceleration time and mortality risk in older adults.

BACKGROUND Pulmonary artery acceleration time (PAAT) is an echocardiographic measure associated with pulmonary artery pressure. Although reduced PAAT has been linked to pulmonary hypertension and adverse outcomes in selected patient populations, less is known about its prognostic significance in community-dwelling olde...

J. A. Nations, Federico E. Mordini, R. Khosla et al. · 0 citations
Open access Oct 2026

Long-Term Safety and Procedural Performance of an Interatrial Shunt for Heart Failure According to Ejection Fraction.

BACKGROUND Long-term device durability and phenotype-specific safety outcomes after interatrial shunting require further characterization. OBJECTIVES This study aimed to evaluate the procedural success, device durability, and heart failure (HF) phenotype-specific safety outcomes of an interatrial shunt in the RELIEVE...

J. Rodés-Cabau, Gregg W. Stone, S. Kar et al. · 1 citation
Open access Aug 2026

Integrated miRNA-cytokine profiling reveals a molecular signature of cachexia in patients with chronic heart failure

Abstract Introduction Cardiac cachexia (CC) complicates chronic heart failure (CHF). Circulating microRNAs (miRNAs) and cytokines, such as growth differentiation factor-15 (GDF-15) and fibroblast growth factor-21 (FGF-21), may reflect the catabolic-anabolic imbalance and structural remodelling associated with this synd...

Federica Tambaro, G. Imbimbo, Carmen Gallicchio et al. · 0 citations
Open access Aug 2026

The C-MIC II Follow-Up Study: Safety and Efficacy Results 12 months After Deactivation of Cardiac Microcurrent Therapy.

BACKGROUND The C-MIC II trial demonstrated benefits of 6 months of cardiac microcurrent (C-MIC) therapy in patients with non-ischemic heart failure with reduced ejection fraction (HFrEF). The prospective C-MIC II Follow-Up Study evaluates safety and efficacy outcomes post-device deactivation. METHODS Primary safety-r...

J. Rame, D. Kosevic, T. Kovačević-Preradović et al. · 0 citations
Open access Aug 2026

Diurnal variation in left atrial pressure in ambulatory patients with chronic heart failure.

Using direct ambulatory intracardiac LAP monitoring, consistent diurnal variation with higher evening pressures was observed, largely unchanged by diuretic dose or dosing schedule, atrial fibrillation, or association with ADHF events.

Yuval Amir, A. Shaul, O. Koren et al. · 0 citations
Open access Jul 2026

Spironolactone in the Treatment of Heart Failure with Mildly Reduced or Preserved Ejection Fraction: Design and Baseline Characteristics of the SPIRIT-HF-DZHK08 Trial.

SPIRIT-HF addresses key evidence gaps for spironolactone in high-risk HFpEF/HFmrEF, and could inform guideline recommendations on MRA use in this cohort.

D. Zurkan, B. Pieske, J. Petutschnigg et al. · 1 citation

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