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Author

Stefan Frantz

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Open access Sep 2026

Discordance between N-terminal pro-B-type natriuretic peptide and left ventricular end-diastolic pressure in suspected heart failure with a preserved ejection fraction: implications for diagnosis and prognosis.

BACKGROUND Diagnosing heart failure with preserved ejection fraction (HFpEF) remains challenging, as natriuretic peptides and resting haemodynamic measurements reflect complementary but incomplete aspects of myocardial stress and filling pressure. METHODS In this prospective all-comer cohort (UKSH-Trial registration...

Gülmisal Güder, S. Störk, Stefan Frantz et al. · 0 citations
Open access Jul 2026

Longitudinal trajectories of neurodegenerative biomarkers in the blood of patients with chronic heart failure

Serial biomarker assessment provided stronger prognostic information than baseline measurements alone in clinically stable patients with chronic HF, and longitudinal increases in circulating amyloid-β peptides associated with cognitive decline, structural brain changes, and mortality.

J. Traub, Anna Frey, G. Homola et al. · 0 citations

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