Outcomes for patients with resectable head and neck squamous cell carcinoma (HNSCC) remain suboptimal despite multimodal therapy, with high rates of recurrence and patients suffering from toxicity of treatments. Immune checkpoint inhibitors, which have transformed the management of recurrent and metastatic disease, hav...
Marius Hörner, Stefan Hartmann, Douglas R. Adkins et al.· Cancer· 0 citations
To develop and empirically characterize a domain-specific, block-structured annotation schema and an expert-annotated reference corpus for German-language head and neck squamous cell carcinoma (HNSCC) pathology reports. We retrieved 631 pathology reports from 145 patients treated at University Hospital Würzburg between...
Sebastian Gubik, Franziska Seger, Andreas Vollmer et al.· BMC Research Notes· 0 citations
A translational framework combining patient-centric benchmarking with a pan-cancer pharmacogenomic atlas of patient-derived organoids and a deep learning model integrating transcriptomic and chemical information to predict drug response and prioritize therapies is introduced, supporting NELLY as a promising framework f...
C. Peralta Viteri, N. Harnischfeger, Lili Szabo et al.· bioRxiv· 0 citations
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