Theoretical Framework for Predicting Dynamic Covalent Exchange Based on Proton Affinities and Proton-Transfer Assistance.
We provide design principles for predicting bond exchange kinetics in acylsemicarbazide (ASC)-based systems that can be applied to tuning the properties of dynamic networks. Because of their capability of dynamic and reversible bond dissociation, ASCs are promising motifs in the design of tunable dynamic covalent netwo...