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Author

Stefan Rubner

2 papers indexed here

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Open access Jan 2026

Comparison of THP‐1 Subtypes Reveals Differences on Transcriptomic and Protein Expression Level Throughout Their Immunological Differentiation

Intensive usage of cancer cell lines as cellular model system in cancer research caused the generation of variant subtypes during the last decades. Genetic aberrations, altered transcriptomic profiles as well as changed protein expression have been reported for diverse cancer cell lines resulting in hampered reproducib...

Sabine Klatt, Gudrun Marquardt, M. Faxel et al. · 0 citations
Open access Aug 2026

Adaptation of Non-Invasive Cancer Cells to 3D Collagen I Microenvironment Induces Transcriptional Reprogramming Accompanied by a More Complex RNA Landscape

Nowadays, most cancer research still depends on traditional cell culture in Petri dishes or cell culture flasks which do not have the ability to mimic physiological-like conditions in vitro. However, the behavior of cancer cells strongly relies on the interaction with their extracellular microenvironment. Consequently,...

Theresa Wießner-Kroh, Stefanie Hübschmann, Gudrun Marquardt et al. · 0 citations

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