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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Stephan C. Schürer

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3 papers indexed here

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Open access Oct 2026

Interactive Data Integrator for Uniform Data Processing in the MorPhiC Program

We present an interactive Data Integrator to facilitate uniform data processing and integration with datasets generated by the NIH funded MorPhiC (Molecular Phenotypes of Null Alleles in Cells) program. In the dataset identification step, users can select published bulk RNA sequencing (RNA-seq) datasets generated by th...

Patrick McKeever, Jesse Flores, Dylan S. Baker et al. · 0 citations
Jul 2026

Abstract B085: Selective oral STK17A inhibitor UMF814A targets a previously unrecognized dark kinase vulnerability in spliceosome-mutant MDS and AML

Myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML) remain therapeutically challenging, particularly in patients with spliceosome-mutant disease, where effective targeted options are lacking. Mutations in SF3B1, SRSF2, and U2AF1 define a biologically distinct subset associated with aberrant RNA splic...

E. Spinetti, C. C. Pastrana, E. Bravo et al. · 0 citations
Open access Jul 2026

From Ternary Modeling to Predictive PROTAC Design: A Computational Perspective

A Perspective on computational PROTAC methodologies published from 2019 to the present is presented, organizing the field into two complementary streams: constraint-driven, physics-based workflows that assemble and refine ternary complex models by enforcing geometric feasibility and evaluating pose stability using dock...

Joseph M. Schulz, R. Reynolds, S. Schürer · 0 citations

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