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Author

Stephen S. Rich

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Open access Aug 2026

Genetic association stratified by HLA-DR3 and HLA-DR4 status reveals heterogeneity in pathways of progression to type 1 diabetes.

AIMS/HYPOTHESIS There are substantial differences in the clinical presentation of type 1 diabetes depending on the first-developing autoantibody, although the underlying mechanisms are poorly understood. The DR3-DQ2 (DR3) and DR4-DQ8 (DR4) haplotypes at the MHC locus associate with GADA and IAA as the first-developing...

A. Luckett, Carolyn McGrail, K. Murrall et al. · 0 citations

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