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Steven H. Spoel

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Open access Aug 2026

HECT-type ligases facilitate autoubiquitination and degradation of other ubiquitin ligases to activate plant immunity

The ubiquitin-proteasome system (UPS) serves as the primary proteolytic machinery in eukaryotes, governing intracellular protein turnover to maintain proteome homeostasis. In plants, the HECT-type UPL3/4 ubiquitin ligases play vital roles in developmental and immune signaling. After ubiquitination by pathway-specific E...

Zhi-Shuo Wang, Robert O. Mason, Heather Grey et al. · 0 citations

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