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Steven Ochoa

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Open access Sep 2026

CompELS vs SELEX: Comparative Aptamer Discovery Integrating Rational Libraries and Enzymatic Elution

Aptamers are oligonucleotides that fold into structures with target-binding activity comparable to antibodies, yet their discovery remains laborious and inconsistent. Traditional Systematic Evolution of Ligands by Exponential Enrichment (SELEX) screening often relies on randomized sequence libraries, repeated amplifi...

Steven Ochoa, V. Milam · 0 citations

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