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Su-Zi Choi

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Open access Oct 2026

TRPML3 and TRPML1/3 differentially regulate unconventional MIF secretion through TMED10 and secretory autophagy

ABSTRACT The intracellular Ca2+ channel TRPML3 regulates autophagy by multimerization in a phosphoinositide (PIP)-dependent manner; however, its role in other membrane dynamics remains unclear. Here, we report that TRPML3 regulates type III unconventional protein secretion (UcPS) through two distinct pathways: TMED10-c...

Jiwoo Park, Jin Kwon, Su-Zi Choi et al. · 0 citations

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