Sudha Jumani Sudha Jumani

Targeting the P2X7–NLRP3 Inflammasome Axis in Obesity: Circadian Regulation of Metabolic Inflammation and Disease Progression

Obesity has become a significant public health issue in both industrialized and developing nations, growing substantially over recent decades. Emerging evidence supports a central role for the purinergic P2X7 receptor along with the NLRP3 inflammasome as intermediary mediators linking metabolic stress and inflammatory...