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Author

Sujoy Ghosh

2 papers indexed here

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Open access Aug 2026

Multi-omics approaches reveal direct NF-κB p65 target genes in pancreatic islets during cytokine exposure and in Type 1 diabetes

Autoimmune diseases, including Type 1 diabetes (T1D), are often characterized by overactive inflammatory signaling pathways. The pro-inflammatory cytokine interleukin-1β (IL-1β) elicits global gene expression changes in islet β-cells which overlap with islets obtained from human donors with T1D. The direct transcriptio...

Thomas M. Martin, Susan J. Burke, Heidi M. Batdorf et al. · 0 citations
Open access Jul 2026

Spermidine targets GGA-rich small RNAs for virulence regulation

Summary Spermidine (SPD), a polyamine essential for various biological processes, has long been recognized as a signaling molecule. Yet, its specific molecular targets and mechanisms of action remain elusive. In this study, we uncover a previously unknown mechanism whereby SPD selectively binds to small regulatory RNAs...

Chao Wang, Xiaoling Liu, Changqing Chang et al. · 0 citations

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