Open access
Jul 2026
Chemical features consistently associated with kinase inhibitor activity: a cross-target SHAP analysis under scaffold-split evaluation.
Findings indicate that kinase QSAR models share a low-magnitude consensus descriptor signal across the kinase family, while target-specific features dominate predictive decision boundaries.
A. Salihu, M. Rahama, W. Salleh et al.
· Molecular diversity · 0 citations