Author

Suliman A. Almahmoud

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Open access Oct 2026

Evaluation of 6-substituted coumarins as SARS-CoV-2 main protease inhibitors: enzymatic, cellular, and computational insights

The SARS-CoV-2 main protease (Mpro) plays a crucial role in viral replication, making it an attractive target for antiviral drug development. This study evaluates the inhibitory potential of nineteen 6-substituted coumarin derivatives (1a–p and 2a–c) against Mpro using a FRET-based enzymatic assay. Among them, the chlo...

Ashraf K. El-Damasy, Md Sofequl Islam Mukim, Sangeun Jeon et al. · RSC Advances · 0 citations

Open access 2026

Comprehensive Chemical Profile and Anti-Infective Properties of Cymbopogon schoenanthus L.: Phytochemical Analysis, In Silico Investigations, and Evaluation of Anti-SARS-CoV-2, Antimicrobial, and Antibiofilm Activities.

Current work investigates the phytochemical components and the antioxidant, antimicrobial, antibiofilm, and anti-SARS-CoV-2 effects of Cymbopogon schoenanthus essential oil using both in vitro and in silico methods. Gas chromatography-mass spectrometry analysis identified 23 volatile constituents, with piperitone (32.6...

Hamdoon A. Mohammed, M. Soliman, Shimaa Moawad et al. · Anais da Academia Brasileira... · 0 citations