Development of Chronomodulated Pulsatile Drug Delivery Systems for Improved Therapeutic Efficacy of Antidiabetic Agents
The present investigation was undertaken to develop and assess a film-coated oral tablet of Epalrestat intended for the treatment of diabetes mellitus. Preformulation investigations, including solubility studies, melting point determination, Fourier-transform infrared (FTIR) spectroscopy, and UV spectrophotometric anal...