Refining Selectivity of Branched CAMPs through Modulation of Hydrophobic–Hydrophilic Balance by Incorporation of N‑Terminal ω- Amino Acid Residues
High selectivity for pathogenic strains over mammalian host cells is a fundamental prerequisite for an antimicrobial therapeutic. Hydrophobic–hydrophilic balance has been a cornerstone for modulating AMP performance. Here, we have refined the selectivity of 2BWWR-7dL by modulating the hydrophilic–hydrophobic balance th...