Open access
2026
Epigenetic profiling of CDH1 and NISCH promoter methylation in plasma-derived cell-free DNA for potential diagnosis of lung cancer
Background: DNA methylation is an epigenetic phenomenon in which DNA methyltransferases (DNMTs) add methyl groups at CpG islands of gene promoter regions, and abnormalities in methylation alter gene expression without changing the DNA sequence. The CDH1 and NISCH genes encode tumor suppressor proteins whose promoter hy...
Santosh Kumar, D. Yadav, Seema Singh et al.
· Medical Data Mining · 0 citations