AIM
A hypoxia-responsive drug-loaded liposomal drug delivery system was designed with the aim of effective treatment of breast cancer. This involves the synthesis and characterization of a nitroimidazole derivative incorporated within the optimized nanoprobe co-loaded with berberine and doxorubicin.
BACKGROUND
Breast...
Harshita Singhai, Sunny Rathee, Sarjana Raikwar et al.· Current Cancer Drug Targets· 0 citations
Angiogenesis, the process of forming new blood vessels from pre-existing vasculature, is a tightly regulated physiological process that is essential for embryonic development, wound healing, tissue regeneration, and the maintenance of normal tissue homeostasis. However, its pathological activation plays a pivotal role...
G. Thakur, Sunny Rathee, Sakshi Soni et al.· Current pharmaceutical desig...· 0 citations
The rapid clinical validation of messenger RNA (RNA) during the COVID-19 pandemic has catalyzed a shift from traditional vaccine development toward a versatile, programmable therapeutic platform. This review provides a comprehensive analysis of the mRNA landscape, moving beyond historical milestones to critically evalu...
Utkarsh Sharma, Vishal Pandey, Hrishika Gupta et al.· Current pharmaceutical desig...· 0 citations
The integration of extensive ethnomedicinal knowledge with emerging phytochemical and pharmacological evidence highlights H. coronarium as a promising source of bioactive compounds for drug discovery and identifies current research gaps and future prospects for translating its bioactive molecules into clinically releva...
Vijay Pratap Ahirwar, Sunny Rathee, U. Patil· Mini-Reviews in Medical Chem...· 0 citations
The growing role of next-generation genome-editing technologies, particularly CRISPR-Cas9, in advancing sustainable phytopharmaceutical and nutraceutical research and facilitating the development of high-value medicinal plant resources is highlighted.
Lokendra Soni, Harshita Singhai, Sunny Rathee et al.· Current pharmaceutical desig...· 0 citations
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