Jul 2026
Formulation and Evaluation of Etoposide-loaded Dextran polymeric nanoparticles fabricated with Hyaluronic acid for the treatment of colorectal cancer using network pharmacology, in-silico, in-vitro, and in-vivo approaches.
Etoposide (ETP), a Biopharmaceutics Classification System class IV drug with poor aqueous solubility, demonstrates limited therapeutic efficacy against colorectal cancer (CRC) because of inferior absorption and off-target effects. To deliver drugs specifically to cancer cells that overexpress CD44, this study developed...
Hrushikesh Wagh, Sankha Bhattacharya, P. Sangave et al.
· Journal of drug targeting (P... · 0 citations