Surendar R Jakka

Halogen Bonding as a Molecular Recognition Strategy for Genetic Code Expansion.

Aminoacyl-tRNA synthetases (aaRSs) catalyze the attachment of amino acids (AAs) to their cognate tRNAs during protein synthesis. As aaRSs possess highly selective amino acid-binding sites, a distinct enzyme is generally required for each amino acid in the genetic code. Recently, genetic code expansion (GCE) has emerged...