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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Susan J. Burke

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Open access Aug 2026

Multi-omics approaches reveal direct NF-κB p65 target genes in pancreatic islets during cytokine exposure and in Type 1 diabetes

Autoimmune diseases, including Type 1 diabetes (T1D), are often characterized by overactive inflammatory signaling pathways. The pro-inflammatory cytokine interleukin-1β (IL-1β) elicits global gene expression changes in islet β-cells which overlap with islets obtained from human donors with T1D. The direct transcriptio...

Thomas M. Martin, Susan J. Burke, Heidi M. Batdorf et al. · 0 citations

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