Obesity is frequently accompanied by low-grade systemic inflammation and increased cardiovascular risk. We evaluated whether glucagon-like peptide-1 receptor agonist (GLP-1 RA) exposure was associated with improved long-term outcomes among adults with obesity and C-reactive protein (CRP) levels of 3-10 mg/L. Using the...
Stuti Shah, M. Abusafia, Hesham Sheashaa et al.· American Journal of Cardiolo...· 0 citations
Compared with no LGE, LGE ≥10% was associated with higher risk of the composite endpoint, and higher %LGE ≥10% was associated with higher risk of the composite endpoint.
Susan K. Keen, Stuti Shah, Hesham Sheashaa et al.· Cardiovascular Research· 0 citations
Background Indexing ascending aortic dimensions to height, rather than absolute diameters, may better identify at-risk ascending aortopathy (AA) patients who could benefit from earlier surgery. Objectives This study evaluated whether height-indexed aortic dimensions improve long-term risk stratification in AA patients...
Milind Y Desai, M. Abusafia, S. Jadam et al.· JACC: Advances· 1 citation
Hypertrophic cardiomyopathy (HCM) is a prototypical inherited cardiomyopathy with well-defined sarcomeric genetic underpinnings that make it an attractive target for molecular therapy. We review recent advances in gene-based approaches for HCM, including adeno-associated virus-mediate gene replacement, allele-specific...
Susan K. Keen, Barry Greenberg, M. Desai· i Medicina· 0 citations
Indexed parameters, particularly CSAH, improve risk stratification beyond absolute diameters and highlight size-based differences in AA and provide an individualized precision imaging-based approach to surgical decision-making.
M. Abusafia, S. Jadam, Susan K. Keen et al.· JACC Cardiovascular Imaging· 1 citation
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